
The gold standard in enzymatic debridement. Santyl selectively removes necrotic tissue while preserving healthy granulation tissue for optimal wound healing.
Santyl is an FDA-approved enzymatic debriding ointment containing collagenase, an enzyme derived from Clostridium histolyticum bacteria. It works by breaking down collagen in necrotic tissue, allowing the body to remove dead tissue naturally.
Unlike sharp debridement, Santyl is selective—it only targets necrotic collagen while leaving healthy tissue intact. This makes it ideal for patients who cannot tolerate sharp debridement or for wounds with fragile granulation tissue.
Only removes dead tissue, preserves healthy granulation
Applied once daily under appropriate dressing
Reimbursed under Medicare Part B and most insurance plans

Collagenase breaks down collagen in necrotic tissue
Body naturally removes liquefied necrotic material
Preserved granulation tissue promotes faster healing
Removes yellow slough without sharp instruments
Gentle debridement for bedridden patients
Continuous debridement between visits
Maintains clean wound bed after initial debridement
Our wound care specialists can determine if enzymatic debridement is right for you
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Healix360 Advanced mobile wound care specialists connecting patients with regenerative healing solutions. Medicare Part B accepted.
6618 San Fernando Rd Glendale Ca 91201
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Santyl Collagenase is a revolutionary enzymatic debriding ointment specifically designed to enhance wound healing. By utilizing collagenase, an enzyme derived from Clostridium histolyticum, Santyl effectively breaks down necrotic tissue while preserving healthy tissue, making it an ideal choice for various wound types.
This treatment option is particularly beneficial for patients with chronic wounds, as it promotes a natural healing process. By selectively targeting necrotic collagen, Santyl not only aids in debris removal but also accelerates tissue regeneration, leading to improved patient outcomes.
The benefits of using Santyl Collagenase extend beyond just effective debridement; it also enhances overall wound healing. Patients experience less pain during treatment compared to traditional sharp debridement methods, making it a more comfortable option.
Additionally, Santyl is easy to apply and can be incorporated into a patient's daily wound care routine. Its selective action minimizes trauma to healthy tissue, which is crucial for maintaining a conducive healing environment and reducing the risk of infection.
Patients often have questions regarding the use of Santyl Collagenase, including its effectiveness, application process, and potential side effects. Understanding these concerns is essential for healthcare providers to ensure patients feel informed and confident in their treatment choices.
Common queries include whether Santyl is covered by insurance and how to incorporate it into existing wound care routines. Addressing these questions helps demystify the treatment process and encourages patients to actively participate in their wound healing journey.
Proper application of Santyl Collagenase is crucial for maximizing its benefits. Patients should follow their healthcare provider's instructions regarding the frequency and amount to apply, ensuring that the ointment is spread evenly over the wound site.
Moreover, maintaining a clean and moist wound environment is vital for optimal healing. Patients should be advised to change dressings regularly and monitor for any signs of infection, allowing for timely adjustments in their wound care regimen.