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Enzymatic Debridement

Santyl Collagenase Ointment

The gold standard in enzymatic debridement. Santyl selectively removes necrotic tissue while preserving healthy granulation tissue for optimal wound healing.

What Is Santyl Collagenase?

Santyl is an FDA-approved enzymatic debriding ointment containing collagenase, an enzyme derived from Clostridium histolyticum bacteria. It works by breaking down collagen in necrotic tissue, allowing the body to remove dead tissue naturally.

 

Unlike sharp debridement, Santyl is selective—it only targets necrotic collagen while leaving healthy tissue intact. This makes it ideal for patients who cannot tolerate sharp debridement or for wounds with fragile granulation tissue.

 

Selective Action

Only removes dead tissue, preserves healthy granulation

Daily Application

Applied once daily under appropriate dressing

Medicare Covered

Reimbursed under Medicare Part B and most insurance plans

Hand applying Santyl collagenase ointment to a wound on the wrist, demonstrating enzymatic debridement for effective wound care.

Quick Navigation to Santyl Collagenase Ointment Sections

Enzyme Action

Collagenase breaks down collagen in necrotic tissue

Debris Removal

Body naturally removes liquefied necrotic material

Healthy Growth

Preserved granulation tissue promotes faster healing

Ideal Wounds for Santyl

Diabetic Ulcers with Slough

Removes yellow slough without sharp instruments

Pressure Ulcers

Gentle debridement for bedridden patients

Venous Leg Ulcers

Continuous debridement between visits

Post-Surgical Wounds

Maintains clean wound bed after initial debridement

Ask About Santyl for Your Wound

Our wound care specialists can determine if enzymatic debridement is right for you

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25+

YEARS OF EXPERIENCE

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ABOUT OUR MEDICAL

We're Putting Your Comfort List

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OUR TESTIMONIALS

Happy Client's Review

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Smiling healthcare professional in a white coat, representing the compassionate care and expertise of Healix360 in wound care services.

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Jimmy Hendrick

HEART PATIENT

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Terresa Watson

DENTAL PATIENT